Host:
Rabbit
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Reactivity:
Human, Mouse, Rat
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Buffers:
0.1 mg in 0.1 ml (1 mg/ml) in PBS containing 0.02% sodium azide.
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Storage:
For long term storage -20 degrees celcius is recommended. Stable at -20 degrees celcius for at least 1 year.
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Application:
WB: 1:1,000
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Western blot of FBG3 antibody (1:500 dilution) performed from 30 ug of recombinant human full-length FBG3 protein.
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Immunogen:
Reacts with residues 103-119 (EWKVEDLSRDQRKEFPN) of the human FBG3 protein. High cross reactivity: 94% identical to mouse and rat FBG3.
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Description:
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.24348.jpg
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References:
- Ilyin GP, Serandour AL, Pigeon C, Rialland M, Glaise D, and Guguen-Guillouzo C: A new subfamily of structurally related human F-box proteins. Gene. Aug 21;296(1-2): 11-20 (2002).
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For Research Use Only. Not for Diagnostic or Therapeutic Use.
Purchase does not include or carry any right to resell or transfer this product either as a stand-alone product or as a component of another product. Any use of this product other than the permitted use without the express written authorization of Orbigen, Inc. is strictly prohibited
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