Animal ID:
RB0391-0392
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Host:
Rabbit
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Reactivity:
human
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Buffers:
Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
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Storage:
Maintain refrigerated at 2-8ºC for up to 6 months. For long term storage store at -20ºC. Avoid repeated freeze-thaw cycles.
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Application:
Tested by peptide-specific ELISA (1:1,000).
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Immunogen:
KLH conjugated synthetic peptide comprised of amino acids 11 - 25 [FLERLEARGGREGAV] of the human protein tyrosine phosphatase non-receptor type 18 (PTPN18) protein.
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Accession number:
NM_011206
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Description:
Protein tyrosine phosphatase non-receptor type 18 (PTPN18) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN18 contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. PTPN18 is mainly expressed in brain, colon tissues, and several different tumor-derived cell lines.
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Alternative Name(s):
BDP1, brain-derived phosphatase
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References:
- Kim YW, Wang H, Sures I, Lammers R, Martell KJ, Ullrich A: Characterization of the PEST family protein tyrosine phosphatase BDP1. Oncogene 13(10): 2275-2279 (1996).
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For Research Use Only. Not for Diagnostic or Therapeutic Use.
Purchase does not include or carry any right to resell or transfer this product either as a stand-alone product or as a component of another product. Any use of this product other than the permitted use without the express written authorization of Orbigen, Inc. is strictly prohibited
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