Animal ID:
RC40104
|
Host:
Chicken
|
Reactivity:
human
|
Buffers:
Purified chicken polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
|
Storage:
Maintain refrigerated at 2-8ºC for up to 6 months. For long term storage store at -20ºC. Avoid repeated freeze-thaw cycles.
|
Application:
Tested by peptide-specific ELISA (1:1,000).
|
|
Immunogen:
Partial protein comprised of amino acids 616 - 728 of the human MAP/microtubule affinity-regulating kinase 3 (MARK3) protein.
|
Accession number:
NM_006035
|
Description:
CDC42 binding protein kinase beta (CDC42BPB) is a member of the serine/threonine portein kinase family. CDC42BPB contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of CDC42BPB is most closely related to that of myotonic dystrophy kinase-related ROK. CDC42BPB seems to act as a downstream effector of Cdc42 in cytoskeletal reorganization.
|
Alternative Name(s):
MRCKB, KIAA1124, DMPK-like, MRCK beta
|
References:
- Moncrieff CL, Bailey ME, Morrison N, Johnson KJ: Cloning and chromosomal localization of human Cdc42-binding protein kinase beta. Genomics 57(2): 297-300 (1999).
- Leung T, Chen XQ, Tan I, Manser E, Lim L: Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization. Mol. Cell. Biol. 18(1): 130-140 (1998).
|
For Research Use Only. Not for Diagnostic or Therapeutic Use.
Purchase does not include or carry any right to resell or transfer this product either as a stand-alone product or as a component of another product. Any use of this product other than the permitted use without the express written authorization of Orbigen, Inc. is strictly prohibited
|
|
