Animal ID:
RC40104
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Host:
Rabbit
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Reactivity:
mouse
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Buffers:
Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
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Storage:
Maintain refrigerated at 2-8ºC for up to 6 months. For long term storage store at -20ºC. Avoid repeated freeze-thaw cycles.
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Application:
Tested by peptide-specific ELISA (1:1,000).
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Immunogen:
KLH conjugated synthetic peptide comprised of amino acids 26 - 36 [YRQVSNKLKKR] of the mouse "factor 8-associated gene A (F8a, HAP40)" protein.
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Accession number:
NM_007978
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Description:
Factor 8-associated gene A (F8a, HAP40) is a 40-kDa Huntingtin-associated protein which is likely to contribute to the function of normal huntingtin and is a candidate for involvement in the aberrant nuclear localization of mutant huntingtin found in degenerating neurons in Huntington's disease. HAP40 is encoded entirely within intron 22 of the factor VIII gene, is transcribed in the direction opposite of factor VIII and spans less than 2 kb . HAP40 is abundantly expressed in a wide variety of cell types but its biological function is unknown.
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Alternative Name(s):
Huntingtin-associated protein, HAP40, DXS522E, factor VIII intron 22 protein
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References:
- Peters MF, Ross CA: Isolation of a 40-kDa Huntingtin-associated protein. J. Biol. Chem. 276(5): 3188-3194 (2001).
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For Research Use Only. Not for Diagnostic or Therapeutic Use.
Purchase does not include or carry any right to resell or transfer this product either as a stand-alone product or as a component of another product. Any use of this product other than the permitted use without the express written authorization of Orbigen, Inc. is strictly prohibited
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